Ethanone, 2-methoxy-1-[4-(trifluoromethyl)phenyl]-
2-Methoxy-1-(4'-trifluoromethyl)phenylethanone
CAS: 26771-69-7
Molecular Formula: C10H9F3O2
Ethanone, 2-methoxy-1-[4-(trifluoromethyl)phenyl]- - Names and Identifiers
| Name | 2-Methoxy-1-(4'-trifluoromethyl)phenylethanone |
| Synonyms | 2-Methoxy-1-(4'-trif 2-Methoxy-4'-trifluoromethylacetophenone 2-Methoxy-1-(4'-trifluoromethyl)acetophenone 2-Methoxy-1-(4'-trifluoromethyl)phenylethanone 2-Methoxy-1-[4-(trifluoromethyl)phenyl]ethanone Ethanone, 2-methoxy-1-[4-(trifluoromethyl)phenyl]- ethanone, 2-methoxy-1-[4-(trifluoromethyl)phenyl]- |
| CAS | 26771-69-7 |
| InChI | InChI=1/C10H9F3O2/c1-15-6-9(14)7-2-4-8(5-3-7)10(11,12)13/h2-5H,6H2,1H3 |
Ethanone, 2-methoxy-1-[4-(trifluoromethyl)phenyl]- - Physico-chemical Properties
| Molecular Formula | C10H9F3O2 |
| Molar Mass | 218.17 |
| Density | 1.23g/cm3 |
| Melting Point | 50-52°C |
| Boling Point | 259.282°C at 760 mmHg |
| Flash Point | 107.352°C |
| Vapor Presure | 0.013mmHg at 25°C |
| Refractive Index | 1.45 |
Ethanone, 2-methoxy-1-[4-(trifluoromethyl)phenyl]- - Introduction
2-Methoxy-1-(4 '-trifluoromethyl)phenylethanone is an organic compound with the chemical formula C10H9F3O2. It is a white crystalline solid with blue fluorescence.
2-Methoxy-1-(4 '-trifluoromethyl)phenylethanone can be used as drug intermediates and Organic Synthesis Reagents. It is often used in the preparation of compounds containing aromatic rings in drug synthesis, such as drugs, pesticides, etc. In addition, it can also be used as an oxidizing agent and a reducing agent in organic synthesis.
There are many methods for preparing 2-Methoxy-1-(4 '-trifluoromethyl)phenylethanone, and a common method is obtained by ketolization reaction. The specific step is to first react 4 '-trifluoromethylbenzaldehyde and methanol under alkaline conditions to obtain the corresponding alcohol, and then react with thionyl chloride to generate the target product.
Regarding safety information, 2-Methoxy-1-(4 '-trifluoromethyl)phenylethanone is relatively safe under correct operation, but it still needs to be used carefully. It may be irritating to the eyes, skin and respiratory system, so appropriate personal protective equipment such as gloves, goggles and protective masks should be worn during operation. In addition, contact with oxidizing agents and strong acids should be avoided to avoid the production of hazardous substances. If necessary, it is recommended to operate in a well-ventilated environment.
2-Methoxy-1-(4 '-trifluoromethyl)phenylethanone can be used as drug intermediates and Organic Synthesis Reagents. It is often used in the preparation of compounds containing aromatic rings in drug synthesis, such as drugs, pesticides, etc. In addition, it can also be used as an oxidizing agent and a reducing agent in organic synthesis.
There are many methods for preparing 2-Methoxy-1-(4 '-trifluoromethyl)phenylethanone, and a common method is obtained by ketolization reaction. The specific step is to first react 4 '-trifluoromethylbenzaldehyde and methanol under alkaline conditions to obtain the corresponding alcohol, and then react with thionyl chloride to generate the target product.
Regarding safety information, 2-Methoxy-1-(4 '-trifluoromethyl)phenylethanone is relatively safe under correct operation, but it still needs to be used carefully. It may be irritating to the eyes, skin and respiratory system, so appropriate personal protective equipment such as gloves, goggles and protective masks should be worn during operation. In addition, contact with oxidizing agents and strong acids should be avoided to avoid the production of hazardous substances. If necessary, it is recommended to operate in a well-ventilated environment.
Last Update：2024-04-09 20:52:54
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